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KMID : 1007520030120020183
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Food Science and Biotechnology
2003 Volume.12 No. 2 p.183 ~ p.186
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Inhibitory Effect on Aflatoxin B_1-8,9-epoxide Formation and Anti-complementary Activity of Methanol Extract from Hericium erinaceus Cultivated with Artemisia iwayomogi
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Lee, Sung-Eun
Jeong, Jae-Hyun/Kim, Dong-Goo/Choi, Won-Sik
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Abstract
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Effects of methanol extracts from Artemisa iwayomogi (AI), Ganoderma lucidum (GL), Hericium erinaceus (HE), G. lucidum cultivated with A. iwayomogi (GLA), and H. erinaceus cultivated with A. iwayomogi (HEA) on biotransformation of aflatoxin B_1 into aflatoxin B_1-8, 9-epoxide (AFBO) were evaluated. HEA showed the most potent inhibitory effect on AFBO formation, whereas that of HE was lower, possibly due to the changes in chemical components of the culture broth after the addition of AI. HEA also had stronger anti-complementary activity than HE. These results indicate the cultivation of HE with AI enhanced cancer preventive activity and host defense system. Anti-complementary activity and inhibitory effect on the AFBO formation of GLA were lower than those of GL. Low anti-complementary activities should specify low inhibitory effects on AFBO formation.
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KEYWORD
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